Selected research highlights
The following journal publications, posters and presentations/discussions about fibrolamellar carcinoma and related topics have been recommended by our scientific advisors:
Multi-omic analysis of microRNA-mediated regulation reveals a proliferative axis involving miR-10b in fibrolamellar carcinomaApril 28, 2022 │ Francisco, … , Bardeesy & Sethupathy
A framework for fibrolamellar carcinoma research and clinical trialsFebruary 22, 2022 │ Dinh, Utria, Barry, Ma, Abou- Alfa, Gordan, Jaffee, Scott, Zucman- Rossi, O’Neill, Furth & Sethupathy
Fibrolamellar carcinoma: An entity all its ownJuly 18, 2021 │ O'Neill, Church, Perez-Atayde, ... & Vakili
Identification of Novel Therapeutic Targets for Fibrolamellar Carcinoma Using Patient Derived Xenografts and Direct from Patient ScreeningJune 14, 2021 │ Lalazar, Requena, ... & Simon
Predictors of Outcome in Patients With Fibrolamellar Carcinoma: Analysis of the National Cancer DatabaseFebruary 5, 2020 │ Assi, Mukherjee, Machiorlatti, Vesely, Pareek & Hatoum
MicroRNA-375 Suppresses the Growth and Invasion of Fibrolamellar CarcinomaFebruary 11, 2019 │ Dinh, Jewell, ... & Sethupathy
Road map for fibrolamellar carcinoma: progress and goals of a diversified approachJanuary 31, 2019 │ Kastenhuber, Craig, ... & Abou-Alfa
CRISPR/Cas9 Engineering of Adult Mouse Liver Demonstrates that the DNAJB1-PRKACA Gene Fusion Is Sufficient to Induce Tumors Resembling Fibrolamellar Hepatocellular CarcinomaDecember 1, 2017 │ Engelholm, Riaz, ... & Frödin
The genomic landscape of fibrolamellar hepatocellular carcinoma: whole genome sequencing of ten patientsDecember 1, 2014 │ Darcy, Chiaroni-Clarke, ... & Simon
Detection of a recurrent DNAJB1-PRKACA chimeric transcript in fibrolamellar hepatocellular carcinomaFebruary 28, 2014 │ Honeyman, Simon, ... & Simon
Gemcitabine-Oxaliplatin-Lenvatinib (GEMOX-LEN) For Unresectable Fibrolamellar Carcinoma: Promising Results in First 16 PatientsMay 1, 2021 │ Reid Davison, Paul Kent
Seeking a Cure: The Promise of ImmunotherapyJune 24, 2021 │ Elizabeth Jaffee, Paul Thomas & Mark Furth
Detailed research listing
Click here to view a complete tabular listing of published scientific articles about FLC.