Generation of T cells with specificity to FLC’s chimeric fusion
Timeframe: 2016 – 2017 Goals: Determine if T cells can be generated that react to FLC’s characteristic fusion protein Principal Investigator: Ephraim Fuchs, MD Study overview: In FLC, the characteristic DNAJB1-PRKACA fusion creates a novel protein with a unique amino acid sequence occurring at the junction of these two proteins. This unique amino acid sequence …