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Goal: Model development Principal Investigator: Nabeel Bardeesy, PhD Grant length: One year Study overview: Cell line models and patient-derived xenographs (PDXs) are important tools that researchers can use to study disease. For FLC research to move forward, stable, reliable, patient-derived cell lines that truly represent the human disease are needed. While multiple FLC models have …
Goal: Assess potential to induce immune response with a FLC therapeutic vaccine Principal Investigator: Mark Yarchoan, MD and Marina Baretti, MD Grant length: Two years Study overview: This grant allows Dr. Mark Yarchoan and Dr. Marina Baretti of Johns Hopkins University to keep JHU’s successful “peptide vaccine” clinical trial open to enrollment by fibrolamellar patients. …
Goals: Assess the potential of a FLC therapeutic vaccine to prevent disease recurrence Principal Investigators: Jens Bauer, PhD Grant length: Two years Study Details: This study, led by Dr. Jens Bauer of the University Hospital Tübingen, aims to develop a new approach to improve the effectiveness of the anti-FLC vaccines that are under development in …