Disruption of PKA RIα phase separation by the oncogenic fusion protein in FLC
Timeframe: 2021 – 2022 Goal: Elucidate the molecular mechanisms of FLC and identify new pharmacological agents that could lead to new, effective therapeutics Principal Investigator: Jin Zhang, PhD, Vice Chair and Professor of Pharmacology, Department of Pharmacology In recent studies, the investigation team discovered that the presence of the FLC oncogenic fusion protein disrupts a …