Dr. Baretti wins prestigious ASCO award

Congratulations to Marina Baretti, MD of Johns Hopkins University! On May 30, she was recognized with a Career Development Award (CDA) at the 2025 American Society of Clinical Oncology (ASCO) Annual Meeting. This highly prestigious award provides three years of research funding to clinical investigators to establish an independent clinical cancer research program. These awards …

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Grant awarded to Wayne State University

The Fibrolamellar Cancer Foundation is pleased to announce that it has awarded an exploratory research grant to Dr. Hugo Jimenez at Wayne State University to investigate the effectiveness of using low energy electromagnetic fields to treat fibrolamellar carcinoma (FLC). In this study, Dr. Jimenez and his team will conduct initial feasibility testing with a device …

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Clinical trial at Johns Hopkins extended

FCF is pleased to announce that it is funding an extension of a clinical trial at the Johns Hopkins Kimmel Cancer Center in Baltimore, MD that tests the ability of a FLC-specific vaccine to produce an immune response against the disease. With this new funding, the trial will be able to enroll 16 additional patients. …

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New immunotherapy trial underway in Tübingen, Germany

In the video below, Dr. Juliane Walz discusses a new clinical trial that is now open to patient enrollment at The University Hospital Tübingen in Tübingen, Germany. This FusionVAC22_02 clinical trial is designed to test the safety and efficacy of a peptide vaccine to delay or prevent the recurrence of fibrolamellar carcinoma (FLC). The peptide …

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New Clinical Trial: Assisted Suicide of FLC Cancer Cells

Cancers grow through uncontrolled cell proliferation. Repeated rounds of division of single cells to yield “daughter” cells cause tumors to expand exponentially. Cancer therapy aims not only to slow down or prevent cell division, but also to cause the malignant cells to die. Efficient killing is crucial because even a tumor that is barely detectable …

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Review DOD research grants

The U.S. Department of Defense has asked FCF to help to recruit community members to serve as consumer reviewers for the Peer Reviewed Cancer Research Program …

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Fred Hutch publication shows potential of PLK1 inhibition as treatment for FLC

In a recent study funded by FCF, scientists at Fred Hutch Cancer Center in Seattle, Washington outlined the potential importance of Polo-like kinase 1 (PLK1) as a promising therapeutic target in FLC. The paper, DNAJ-PKAc fusion heightens PLK1 inhibitor sensitivity in fibrolamellar carcinoma, was published on April 24 in the journal Gut. The effort was …

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Partnership with Dialectic Therapeutics enables launch of clinical trial

FCF is pleased to announce its partnership with Dialectic Therapeutics to supply an experimental drug, DT2216, for a planned clinical trial for fibrolamellar patients. Under the agreement, FCF will fund the production of the DT2216 necessary to support the trial. The Foundation’s funding of the manufacturing costs of the drug was crucial to ensure the …

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Congratulations to Dr. Juliane Walz!

Congratulations to Dr. Juliane Walz of the University of Tübingen who was recently honored at überDACHt – Roche Science & Innovation Summit with the “Best Overall Award” for the upcoming fibrolamellar clinical trial, FusionVac_22_02. The event in Basel, Switzerland on March 21, 2025, brought together researchers from Germany, Austria and Switzerland to discuss innovations in …

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