Date(s) - September 29, 2022
8:00 pm EDT - 9:00 pm EDT
This webinar, hosted by FCF in collaboration with TargetCancer Foundation and Angiosarcoma Awareness, is the second of four webinars in which we explore how precision cancer medicine is being applied to rare cancers.
A major mode of precision cancer medicine entails identification of all mutations in a patient’s tumor cells that are potentially associated with cancerous growth. A key goal is to develop targeted cancer therapies that attack specific molecular drivers of cancer, and to use these treatments specifically in those patients whose cancers are most likely to respond.
This particular webinar will explore the application of functional precision medicine to rare cancers, a strategy whereby live tumor cells from affected individuals are directly treated with drugs to provide immediate, personalized information to guide therapy. Increasingly, the clinical community has realized that more personalized approaches to therapy are often needed to provide additional information regarding tumor vulnerabilities and improve treatment outcomes. Key issues for discussion in this webinar will include:
- Defining functional precision medicine
- Understanding “-omics” profiling, the global analyses of tumors
- Gene expression (“transcriptome”)
- Protein expression (“proteome”)
- Chromatin regulation (“epigenome”)
- Tumor metabolism (“metabolome”)
- Determining global cancer dependencies
- What genes does a cancer require to grow and survive?
- What existing drugs and compounds can kill or halt the growth of a cancer?
- Identifying cancer pathways
- Finding useful drug targets in the downstream biochemical and metabolic pathways by which cancer drivers promote tumor cell growth and survival
- Performing individualized drug testing
- Feasibility and predictive value of personalized assays on patient-derived cancer specimens
- Understanding activities being done today, and the prospects for future development
- For targeted therapy
- For immunotherapy.
Registration for this event will be opening soon!