Timeframe: 2014 – 2015
Goal: Investigate the potential of radioactive iodine as a therapeutic in FLC
Principle Investigator: Nancy Carrasco, MD, Professor, Cellular and Molecular Physiology, Yale University (Currently at Vanderbilt University)
FLC cells express high levels of the iodine transporter NIS, raising the possibility that radioactive iodine may be a potential therapeutic for FLC. Radioactive iodine has a long and effective history as a treatment for thyroid cancer, which effectively takes in iodine. This study investigated whether FLC cells readily uptake iodine and if radioactive iodine may serve as an effective therapeutic for FLC patients.
[NOTE: Use of radioactive iodine on several patients did not confirm this theory and the project was terminated]