Modulating stromal-immune cell interactions to activate anti-tumor immunity to fibrolamellar carcinoma
Timeframe: 2020 Goal: Assess whether suppressing checkpoints or signaling by a specific chemokine (CXCL12) can enhance immune response in FLC Principal Investigator: Venu Pillarisetty, MD Study overview: Immunotherapy, harnessing the patient’s immune system to precisely target cancer cells, has emerged as a promising approach to treat many cancers. It has been discovered that fibrolamellar carcinoma …